Emerging paradigms in pre-clinical screening models for drugs acting against diabetes: Delving into complex approaches and advancements

Delving into BioMEMS.

Delving into somatic variation in sporadic melanoma.

Melanoma, the most aggressive form of skin cancer, has increased in incidence more rapidly than any other cancer. The completion of the human genome project and advancements in genomics technologies has allowed us to investigate genetic alterations of melanoma at a scale and depth that is unprecedented. Here, we survey the history of the different approaches taken to understand the genomics of ...

Emerging paradigms in immunonutrition.

Nutritional immunology is the study of the relationship between food and the immune system. It evolved with the study of immune deficiencies caused by malnutrition. However, because of technological advances made over the past few decades, malnutrition is no longer the main cause of lowered immune status in otherwise healthy people/animals. Rather, life stage (neonate or old age) and natural st...

Delving into the Successes and Failures Of

In this day and age, the Internet has become an integral part of our lives. Question and answer (Q&A) networks like Stack Exchange have grown to become major sources of knowledge on the Internet. On the Internet, users devote time into looking for answers to questions they have. Sometimes, these users are able to find these answers and other times they do not, thus wasting their time. If these ...

Clinical Advancements in the Targeted Therapies against Liver Fibrosis

Hepatic fibrosis, characterized by excessive accumulation of extracellular matrix (ECM) proteins leading to liver dysfunction, is a growing cause of mortality worldwide. Hepatocellular damage owing to liver injury leads to the release of profibrotic factors from infiltrating inflammatory cells that results in the activation of hepatic stellate cells (HSCs). Upon activation, HSCs undergo charact...